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Lidocaine Suppresses Viability and Migration of Human Breast Cancer Cells: TRPM7 as a Target for Some Breast Cancer Cell Lines

SIMPLE SUMMARY: The local anesthetic lidocaine suppresses some cancer cell lines but the mechanism is unclear. Melastatin-like transient receptor potential 7 (TRPM7) ion channels play a role in cancer and may be a target for lidocaine. The aim of our study is to test the hypothesis that lidocaine af...

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Detalles Bibliográficos
Autores principales: Liu, Hengrui, Dilger, James P., Lin, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827240/
https://www.ncbi.nlm.nih.gov/pubmed/33435261
http://dx.doi.org/10.3390/cancers13020234