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A Comprehensive Study of the Retinal Phenotype of Rpe65-Deficient Dogs

The Rpe65-deficient dog has been important for development of translational therapies of Leber congenital amaurosis type 2 (LCA2). The purpose of this study was to provide a comprehensive report of the natural history of retinal changes in this dog model. Rpe65-deficient dogs from 2 months to 10 yea...

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Detalles Bibliográficos
Autores principales: Annear, Matthew J, Mowat, Freya M, Occelli, Laurence M, Smith, Alexander J, Curran, Paul G, Bainbridge, James W, Ali, Robin R, Petersen-Jones, Simon M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827248/
https://www.ncbi.nlm.nih.gov/pubmed/33435495
http://dx.doi.org/10.3390/cells10010115