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Vaccinia Virus Protein B18R: Influence on mRNA Immunogenicity and Translation upon Non-Viral Delivery in Different Ocular Cell Types

In the last few years, interest has grown in the use of nucleic acids as an ocular therapy for retinal genetic diseases. Recently, our research group has demonstrated that mRNA delivery could result in effective protein expression in ocular cells following subretinal injection. Yet, although mRNA th...

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Detalles Bibliográficos
Autores principales: Minnaert, An-Katrien, Devoldere, Joke, Peynshaert, Karen, Vercruysse, Laure, De Smedt, Stefaan C., Remaut, Katrien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827308/
https://www.ncbi.nlm.nih.gov/pubmed/33430462
http://dx.doi.org/10.3390/pharmaceutics13010074