Precursor B-ALL Cell Lines Differentially Respond to SYK Inhibition by Entospletinib

Background: Impaired B-cell receptor (BCR) function has been associated with the progress of several B-cell malignancies. The spleen tyrosine kinase (SYK) represents a potential therapeutic target in a subset of B-cell neoplasias. In precursor B-acute lymphoblastic leukemia (B-ALL), the pathogenic r...

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Detalles Bibliográficos
Autores principales: Sender, Sina, Sekora, Anett, Villa Perez, Simon, Chabanovska, Oleksandra, Becker, Annegret, Ngezahayo, Anaclet, Junghanss, Christian, Murua Escobar, Hugo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827334/
https://www.ncbi.nlm.nih.gov/pubmed/33435587
http://dx.doi.org/10.3390/ijms22020592

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827334/
https://www.ncbi.nlm.nih.gov/pubmed/33435587
http://dx.doi.org/10.3390/ijms22020592

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