Mechanisms of Insulin Resistance at the Crossroad of Obesity with Associated Metabolic Abnormalities and Cognitive Dysfunction

Obesity mediates most of its direct medical sequelae through the development of insulin resistance (IR). The cellular effects of insulin occur through two main postreceptor pathways that are the phosphatidylinositol 3-kinase (PI3-K) and the mitogen-activated protein kinase (MAP-K) pathways. Obesity-...

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Detalles Bibliográficos
Autores principales: Barber, Thomas M., Kyrou, Ioannis, Randeva, Harpal S., Weickert, Martin O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827338/
https://www.ncbi.nlm.nih.gov/pubmed/33430419
http://dx.doi.org/10.3390/ijms22020546

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827338/
https://www.ncbi.nlm.nih.gov/pubmed/33430419
http://dx.doi.org/10.3390/ijms22020546

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