Cargando…

The Yin and Yang-Like Clinical Implications of the CDKN2A/ARF/CDKN2B Gene Cluster in Acute Lymphoblastic Leukemia

Acute lymphoblastic leukemia (ALL) is a malignant clonal expansion of lymphoid hematopoietic precursors that exhibit developmental arrest at varying stages of differentiation. Similar to what occurs in solid cancers, transformation of normal hematopoietic precursors is governed by a multistep oncoge...

Descripción completa

Detalles Bibliográficos
Autores principales: González-Gil, Celia, Ribera, Jordi, Ribera, Josep Maria, Genescà, Eulàlia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827355/
https://www.ncbi.nlm.nih.gov/pubmed/33435487
http://dx.doi.org/10.3390/genes12010079