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Cellular and Molecular Mechanisms of R/S-Roscovitine and CDKs Related Inhibition under Both Focal and Global Cerebral Ischemia: A Focus on Neurovascular Unit and Immune Cells

Ischemic stroke is the second leading cause of death worldwide. Following ischemic stroke, Neurovascular Unit (NVU) inflammation and peripheral leucocytes infiltration are major contributors to the extension of brain lesions. For a long time restricted to neurons, the 10 past years have shown the em...

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Detalles Bibliográficos
Autores principales: Le Roy, Lucas, Letondor, Anne, Le Roux, Cloé, Amara, Ahmed, Timsit, Serge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827530/
https://www.ncbi.nlm.nih.gov/pubmed/33429982
http://dx.doi.org/10.3390/cells10010104