Libertellenone H, a Natural Pimarane Diterpenoid, Inhibits Thioredoxin System and Induces ROS-Mediated Apoptosis in Human Pancreatic Cancer Cells

Libertellenone H (LH), a marine-derived pimarane diterpenoid isolated from arctic fungus Eutypella sp. D-1, has shown effective cytotoxicity on a range of cancer cells. The present study is to explore the anticancer effect of LH on human pancreatic cancer cells and to investigate the intracellular m...

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Detalles Bibliográficos
Autores principales: Zhang, Weirui, Zhu, Yuping, Yu, Haobing, Liu, Xiaoyu, Jiao, Binghua, Lu, Xiaoling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827531/
https://www.ncbi.nlm.nih.gov/pubmed/33435380
http://dx.doi.org/10.3390/molecules26020315

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827531/
https://www.ncbi.nlm.nih.gov/pubmed/33435380
http://dx.doi.org/10.3390/molecules26020315

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