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Libertellenone H, a Natural Pimarane Diterpenoid, Inhibits Thioredoxin System and Induces ROS-Mediated Apoptosis in Human Pancreatic Cancer Cells
Libertellenone H (LH), a marine-derived pimarane diterpenoid isolated from arctic fungus Eutypella sp. D-1, has shown effective cytotoxicity on a range of cancer cells. The present study is to explore the anticancer effect of LH on human pancreatic cancer cells and to investigate the intracellular m...
Autores principales: | Zhang, Weirui, Zhu, Yuping, Yu, Haobing, Liu, Xiaoyu, Jiao, Binghua, Lu, Xiaoling |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827531/ https://www.ncbi.nlm.nih.gov/pubmed/33435380 http://dx.doi.org/10.3390/molecules26020315 |
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