Protease Inhibitor Anti-HIV, Lopinavir, Impairs Placental Endocrine Function

Protease Inhibitors (PI e.g., ritonavir (RTV) and lopinavir (LPV)) used to treat pregnant mothers infected by HIV induce prematurity and endocrine dysfunctions. The maintenance of pregnancy relies on placental hormone production (human Chorionic Gonadotrophin (hCG) and progesterone (P4)). Those func...

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Detalles Bibliográficos
Autores principales: Fraichard, Camille, Bonnet-Serrano, Fidéline, Laguillier-Morizot, Christelle, Hebert-Schuster, Marylise, Lai-Kuen, René, Sibiude, Jeanne, Fournier, Thierry, Cohen, Marie, Guibourdenche, Jean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827556/
https://www.ncbi.nlm.nih.gov/pubmed/33445576
http://dx.doi.org/10.3390/ijms22020683

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827556/
https://www.ncbi.nlm.nih.gov/pubmed/33445576
http://dx.doi.org/10.3390/ijms22020683

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