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DNA-Damage-Induced Alternative Splicing of p53

SIMPLE SUMMARY: The tumor suppressor p53 is frequently mutated across numerous cancer types and has an essential role in the response to DNA-damaging agents, such as irradiation. DNA damage can induce different forms of the p53 protein, and the different forms of the p53 protein can elicit distinct...

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Detalles Bibliográficos
Autores principales: Chen, Jing, Zhang, Dadong, Qin, Xiaodi, Owzar, Kouros, McCann, Jennifer J., Kastan, Michael B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827558/
https://www.ncbi.nlm.nih.gov/pubmed/33445417
http://dx.doi.org/10.3390/cancers13020251