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A Set of Cell Lines Derived from a Genetic Murine Glioblastoma Model Recapitulates Molecular and Morphological Characteristics of Human Tumors

SIMPLE SUMMARY: Glioblastoma (GBM) is a highly aggressive and almost inevitably lethal brain tumor. Animal models for GBM are crucial to study how the tumor evolves in vivo and to test novel treatment options. Most currently available models are based on the transplantation of human GBM cells into m...

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Detalles Bibliográficos
Autores principales: Costa, Barbara, Fletcher, Michael N. C., Boskovic, Pavle, Ivanova, Ekaterina L., Eisemann, Tanja, Lohr, Sabrina, Bunse, Lukas, Löwer, Martin, Burchard, Stefanie, Korshunov, Andrey, Coltella, Nadia, Cusimano, Melania, Naldini, Luigi, Liu, Hai-Kun, Platten, Michael, Radlwimmer, Bernhard, Angel, Peter, Peterziel, Heike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827614/
https://www.ncbi.nlm.nih.gov/pubmed/33435218
http://dx.doi.org/10.3390/cancers13020230