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Mitochondrial Cyclosporine A-Independent Palmitate/Ca(2+)-Induced Permeability Transition Pore (PA-mPT Pore) and Its Role in Mitochondrial Function and Protection against Calcium Overload and Glutamate Toxicity

A sharp increase in the permeability of the mitochondrial inner membrane known as mitochondrial permeability transition (or mPT) occurs in mitochondria under the conditions of Ca(2+) and ROS stress. Permeability transition can proceed through several mechanisms. The most common mechanism of mPT is b...

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Detalles Bibliográficos
Autores principales: Mironova, Galina D., Pavlov, Evgeny V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827677/
https://www.ncbi.nlm.nih.gov/pubmed/33440765
http://dx.doi.org/10.3390/cells10010125