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Mitochondrial Cyclosporine A-Independent Palmitate/Ca(2+)-Induced Permeability Transition Pore (PA-mPT Pore) and Its Role in Mitochondrial Function and Protection against Calcium Overload and Glutamate Toxicity
A sharp increase in the permeability of the mitochondrial inner membrane known as mitochondrial permeability transition (or mPT) occurs in mitochondria under the conditions of Ca(2+) and ROS stress. Permeability transition can proceed through several mechanisms. The most common mechanism of mPT is b...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827677/ https://www.ncbi.nlm.nih.gov/pubmed/33440765 http://dx.doi.org/10.3390/cells10010125 |