Investigation of Solubility Behavior of Canagliflozin Hydrate Crystals Combining Crystallographic and Hirshfeld Surface Calculations

Canagliflozin (CG) was a highly effective, selective and reversible inhibitor of sodium-dependent glucose co-transporter 2 developed for the treatment of type 2 diabetes mellitus. The crystal structure of CG monohydrate (CG-H(2)O) was reported for the first time while CG hemihydrate (CG-Hemi) had be...

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Detalles Bibliográficos
Autores principales: Zhu, Yefen, Kang, Yanlei, Zhu, Ling, Yu, Kaxi, Chen, Shuai, Tang, Guping, Hu, Xiurong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827693/
https://www.ncbi.nlm.nih.gov/pubmed/33435602
http://dx.doi.org/10.3390/molecules26020298

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827693/
https://www.ncbi.nlm.nih.gov/pubmed/33435602
http://dx.doi.org/10.3390/molecules26020298

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