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Effectiveness of Columbianadin, a Bioactive Coumarin Derivative, in Perturbing Transient and Persistent I(Na)

Columbianadin (CBN) is a bioactive coumarin-type compound with various biological activities. However, the action of CBN on the ionic mechanism remains largely uncertain, albeit it was reported to inhibit voltage-gated Ca(2+) current or to modulate TRP-channel activity. In this study, whole-cell pat...

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Detalles Bibliográficos
Autores principales: Chang, Wei-Ting, Wu, Sheng-Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827714/
https://www.ncbi.nlm.nih.gov/pubmed/33435511
http://dx.doi.org/10.3390/ijms22020621