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Continuous-Flow Synthesis of Thioureas, Enabled by Aqueous Polysulfide Solution
We have developed the continuous-flow synthesis of thioureas in a multicomponent reaction starting from isocyanides, amidines, or amines and sulfur. The aqueous polysulfide solution enabled the application of sulfur under homogeneous and mild conditions. The crystallized products were isolated by si...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827778/ https://www.ncbi.nlm.nih.gov/pubmed/33435580 http://dx.doi.org/10.3390/molecules26020303 |