Non-Canonical Functions of the ARF Tumor Suppressor in Development and Tumorigenesis

P14ARF (ARF; Alternative Reading Frame) is an extensively characterized tumor suppressor which, in response to oncogenic stimuli, mediates cell cycle arrest and apoptosis via p53-dependent and independent routes. ARF has been shown to be frequently lost through CpG island promoter methylation in a w...

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Detalles Bibliográficos
Autores principales: Lagopati, Nefeli, Belogiannis, Konstantinos, Angelopoulou, Andriani, Papaspyropoulos, Angelos, Gorgoulis, Vassilis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827855/
https://www.ncbi.nlm.nih.gov/pubmed/33445626
http://dx.doi.org/10.3390/biom11010086

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827855/
https://www.ncbi.nlm.nih.gov/pubmed/33445626
http://dx.doi.org/10.3390/biom11010086

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