Validation of an HPLC–MS/MS Method for the Determination of Plasma Ticagrelor and Its Active Metabolite Useful for Research and Clinical Practice

Ticagrelor is an antiplatelet agent which is extensively metabolized in an active metabolite: AR-C124910XX. Ticagrelor antagonizes P2Y12 receptors, but recently, this effect on the central nervous system has been linked to the development of dyspnea. Ticagrelor-related dyspnea has been linked to per...

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Detalles Bibliográficos
Autores principales: Lagoutte-Renosi, Jennifer, Royer, Bernard, Rabani, Vahideh, Davani, Siamak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827928/
https://www.ncbi.nlm.nih.gov/pubmed/33429903
http://dx.doi.org/10.3390/molecules26020278

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827928/
https://www.ncbi.nlm.nih.gov/pubmed/33429903
http://dx.doi.org/10.3390/molecules26020278

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