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Validation of an HPLC–MS/MS Method for the Determination of Plasma Ticagrelor and Its Active Metabolite Useful for Research and Clinical Practice

Ticagrelor is an antiplatelet agent which is extensively metabolized in an active metabolite: AR-C124910XX. Ticagrelor antagonizes P2Y12 receptors, but recently, this effect on the central nervous system has been linked to the development of dyspnea. Ticagrelor-related dyspnea has been linked to per...

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Detalles Bibliográficos
Autores principales:	Lagoutte-Renosi, Jennifer, Royer, Bernard, Rabani, Vahideh, Davani, Siamak
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827928/ https://www.ncbi.nlm.nih.gov/pubmed/33429903 http://dx.doi.org/10.3390/molecules26020278

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