Combinatorial Therapeutic Effect of Inhibitors of Aldehyde Dehydrogenase and Mitochondrial Complex I, and the Chemotherapeutic Drug, Temozolomide against Glioblastoma Tumorspheres

Resident cancer cells with stem cell-like features induce drug tolerance, facilitating survival of glioblastoma (GBM). We previously showed that strategies targeting tumor bioenergetics present a novel emerging avenue for treatment of GBM. The objective of this study was to enhance the therapeutic e...

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Detalles Bibliográficos
Autores principales: Park, Hun Ho, Park, Junseong, Cho, Hye Joung, Shim, Jin-Kyoung, Moon, Ju Hyung, Kim, Eui Hyun, Chang, Jong Hee, Kim, Soo Youl, Kang, Seok-Gu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827959/
https://www.ncbi.nlm.nih.gov/pubmed/33429981
http://dx.doi.org/10.3390/molecules26020282

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827959/
https://www.ncbi.nlm.nih.gov/pubmed/33429981
http://dx.doi.org/10.3390/molecules26020282

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