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Role of Retinoic Acid Signaling, FGF Signaling and Meis Genes in Control of Limb Development

The function of retinoic acid (RA) during limb development is still debated, as loss and gain of function studies led to opposite conclusions. With regard to limb initiation, genetic studies demonstrated that activation of FGF10 signaling is required for the emergence of limb buds from the trunk, wi...

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Detalles Bibliográficos
Autores principales: Berenguer, Marie, Duester, Gregg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827967/
https://www.ncbi.nlm.nih.gov/pubmed/33435477
http://dx.doi.org/10.3390/biom11010080