Development and Characterization of Treprostinil Palmitil Inhalation Aerosol for the Investigational Treatment of Pulmonary Arterial Hypertension

Treprostinil palmitil (TP) is a prodrug of treprostinil (TRE), a pulmonary vasodilator that has been previously formulated for inhaled administration via a nebulizer. TP demonstrates a sustained presence in the lungs with reduced systemic exposure and prolonged inhibition of hypoxia-induced pulmonar...

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Detalles Bibliográficos
Autores principales: Plaunt, Adam J., Islam, Sadikul, Macaluso, Tony, Gauani, Helena, Baker, Thomas, Chun, Donald, Viramontes, Veronica, Chang, Christina, Corboz, Michel R., Chapman, Richard W., Li, Zhili, Cipolla, David C., Perkins, Walter R., Malinin, Vladimir S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7828008/
https://www.ncbi.nlm.nih.gov/pubmed/33430435
http://dx.doi.org/10.3390/ijms22020548

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7828008/
https://www.ncbi.nlm.nih.gov/pubmed/33430435
http://dx.doi.org/10.3390/ijms22020548

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