Counteracting Effects of Glutathione on the Glutamate-Driven Excitation/Inhibition Imbalance in First-Episode Schizophrenia: A 7T MRS and Dynamic Causal Modeling Study

Oxidative stress plays a key role in the pathophysiology of schizophrenia. While free radicals produced by glutamatergic excess and oxidative metabolism have damaging effects on brain tissue, antioxidants such as glutathione (GSH) counteract these effects. The interaction between glutamate (GLU) and...

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Detalles Bibliográficos
Autores principales: Limongi, Roberto, Jeon, Peter, Théberge, Jean, Palaniyappan, Lena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7828075/
https://www.ncbi.nlm.nih.gov/pubmed/33430154
http://dx.doi.org/10.3390/antiox10010075

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7828075/
https://www.ncbi.nlm.nih.gov/pubmed/33430154
http://dx.doi.org/10.3390/antiox10010075

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