Pharmacokinetic—Pharmacodynamic Modeling of Tumor Targeted Drug Delivery Using Nano-Engineered Mesenchymal Stem Cells

Nano-engineered mesenchymal stem cells (nano-MSCs) are promising targeted drug delivery platforms for treating solid tumors. MSCs engineered with paclitaxel (PTX) loaded poly(lactide-co-glycolide) (PLGA) nanoparticles (NPs) are efficacious in treating lung and ovarian tumors in mouse models. The qua...

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Detalles Bibliográficos
Autores principales: Cheng, Shen, Nethi, Susheel Kumar, Al-Kofahi, Mahmoud, Prabha, Swayam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7828117/
https://www.ncbi.nlm.nih.gov/pubmed/33445681
http://dx.doi.org/10.3390/pharmaceutics13010092

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7828117/
https://www.ncbi.nlm.nih.gov/pubmed/33445681
http://dx.doi.org/10.3390/pharmaceutics13010092

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