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PKC Regulates YAP Expression through Alternative Splicing of YAP 3′UTR Pre-mRNA by hnRNP F

The Yes-associated protein (YAP) is a transcriptional co-activator that plays critical roles in organ development and tumorigenesis, and is verified to be inhibited by the Hippo signaling pathway. In the present study, we show that the YAP 3′UTR is alternatively spliced to generate a novel 950 bp 3′...

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Detalles Bibliográficos
Autores principales: Chu, Wing-Keung, Hung, Li-Man, Hou, Chun-Wei, Chen, Jan-Kan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7828143/
https://www.ncbi.nlm.nih.gov/pubmed/33445676
http://dx.doi.org/10.3390/ijms22020694