An Efficient Synthesis of Optically Active [4-(13)C] Labelled Quorum Sensing Signal Autoinducer-2

A new synthetic route for the quorum sensing signal Autoinducer-2 (AI-2) is described and used for the preparation of [4-(13)C]-AI-2 starting from [1-(13)C]-bromoacetic acid. The key step in this process was the enantioselective reduction of an intermediate ketone. This synthesis provides, selective...

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Detalles Bibliográficos
Autores principales: Ascenso, Osvaldo S., Carrau, Gonzalo, Xavier, Karina B., Ventura, M. Rita, Maycock, Christopher D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7828210/
https://www.ncbi.nlm.nih.gov/pubmed/33445716
http://dx.doi.org/10.3390/molecules26020369

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7828210/
https://www.ncbi.nlm.nih.gov/pubmed/33445716
http://dx.doi.org/10.3390/molecules26020369

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