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Hindering triple negative breast cancer progression by targeting endogenous interleukin‐30 requires IFNγ signaling

IL30mRNA expression is associated with the TNBC subtype. IL30 boosts proliferation and migration of TNBC cells and reshapes their immunity gene expression profile. The lack of endogenous IL30 hinders TNBC growth and progression and prolongs host survival. TNBC growth inhibition, due to the lack of e...

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Detalles Bibliográficos
Autores principales: Sorrentino, Carlo, Ciummo, Stefania Livia, D'Antonio, Luigi, Lanuti, Paola, Abrams, Scott I., Yin, Zhinan, Lu, Li‐Fan, Di Carlo, Emma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7828256/
https://www.ncbi.nlm.nih.gov/pubmed/33635005
http://dx.doi.org/10.1002/ctm2.278