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Perlecan in the Natural and Cell Therapy Repair of Human Adult Articular Cartilage: Can Modifications in This Proteoglycan Be a Novel Therapeutic Approach?

Articular cartilage is considered to have limited regenerative capacity, which has led to the search for therapies to limit or halt the progression of its destruction. Perlecan, a multifunctional heparan sulphate (HS) proteoglycan, promotes embryonic cartilage development and stabilises the mature t...

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Detalles Bibliográficos
Autores principales: Garcia, John, McCarthy, Helen S., Kuiper, Jan Herman, Melrose, James, Roberts, Sally
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7828356/
https://www.ncbi.nlm.nih.gov/pubmed/33450893
http://dx.doi.org/10.3390/biom11010092