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Perlecan in the Natural and Cell Therapy Repair of Human Adult Articular Cartilage: Can Modifications in This Proteoglycan Be a Novel Therapeutic Approach?
Articular cartilage is considered to have limited regenerative capacity, which has led to the search for therapies to limit or halt the progression of its destruction. Perlecan, a multifunctional heparan sulphate (HS) proteoglycan, promotes embryonic cartilage development and stabilises the mature t...
Autores principales: | Garcia, John, McCarthy, Helen S., Kuiper, Jan Herman, Melrose, James, Roberts, Sally |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7828356/ https://www.ncbi.nlm.nih.gov/pubmed/33450893 http://dx.doi.org/10.3390/biom11010092 |
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