Lysine Deprivation Induces AKT-AADAT Signaling and Overcomes EGFR-TKIs Resistance in EGFR-Mutant Non-Small Cell Lung Cancer Cells

SIMPLE SUMMARY: In the Asian population, 50–60% of non-small cell lung cancer (NSCLC) patients carry the epidermal growth factor receptor (EGFR) mutation. Although treatment with EGFR-tyrosine kinase inhibitors (EGFR-TKIs) is effective, resistance inevitably occurs. Moreover, previous studies showed...

Descripción completa

Detalles Bibliográficos
Autores principales: Hsu, Chia-Chi, Yang, Albert Ying-Po, Chen, Jui-Yi, Tsai, Hsin-Hui, Lin, Shu-Heng, Tai, Pei-Chen, Huang, Ming-Hung, Hsu, Wei-Hsun, Lin, Anya Maan-Yuh, Yang, James Chih-Hsin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7828377/
https://www.ncbi.nlm.nih.gov/pubmed/33450879
http://dx.doi.org/10.3390/cancers13020272

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7828377/
https://www.ncbi.nlm.nih.gov/pubmed/33450879
http://dx.doi.org/10.3390/cancers13020272

Ejemplares similares