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Lysine Deprivation Induces AKT-AADAT Signaling and Overcomes EGFR-TKIs Resistance in EGFR-Mutant Non-Small Cell Lung Cancer Cells

SIMPLE SUMMARY: In the Asian population, 50–60% of non-small cell lung cancer (NSCLC) patients carry the epidermal growth factor receptor (EGFR) mutation. Although treatment with EGFR-tyrosine kinase inhibitors (EGFR-TKIs) is effective, resistance inevitably occurs. Moreover, previous studies showed...

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Detalles Bibliográficos
Autores principales:	Hsu, Chia-Chi, Yang, Albert Ying-Po, Chen, Jui-Yi, Tsai, Hsin-Hui, Lin, Shu-Heng, Tai, Pei-Chen, Huang, Ming-Hung, Hsu, Wei-Hsun, Lin, Anya Maan-Yuh, Yang, James Chih-Hsin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7828377/ https://www.ncbi.nlm.nih.gov/pubmed/33450879 http://dx.doi.org/10.3390/cancers13020272

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