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Myosin Binding Protein-C Forms Amyloid-Like Aggregates In Vitro

This work investigated in vitro aggregation and amyloid properties of skeletal myosin binding protein-C (sMyBP-C) interacting in vivo with proteins of thick and thin filaments in the sarcomeric A-disc. Dynamic light scattering (DLS) and transmission electron microscopy (TEM) found a rapid (5–10 min)...

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Detalles Bibliográficos
Autores principales: Bobyleva, Liya G., Shumeyko, Sergey A., Yakupova, Elmira I., Surin, Alexey K., Galzitskaya, Oxana V., Kihara, Hiroshi, Timchenko, Alexander A., Timchenko, Maria A., Penkov, Nikita V., Nikulin, Alexey D., Suvorina, Mariya Yu., Molochkov, Nikolay V., Lobanov, Mikhail Yu., Fadeev, Roman S., Vikhlyantsev, Ivan M., Bobylev, Alexander G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7828380/
https://www.ncbi.nlm.nih.gov/pubmed/33450960
http://dx.doi.org/10.3390/ijms22020731