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Mapping the DNA-Binding Motif of Scabin Toxin, a Guanine Modifying Enzyme from Streptomyces scabies

Scabin is a mono-ADP-ribosyltransferase toxin/enzyme and possible virulence factor produced by the agriculture pathogen, Streptomyces scabies. Recently, molecular dynamic approaches and MD simulations revealed its interaction with both NAD(+) and DNA substrates. An Essential Dynamics Analysis identi...

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Detalles Bibliográficos
Autores principales: Vatta, Maritza, Lyons, Bronwyn, Heney, Kayla A., Lidster, Taylor, Merrill, A. Rod
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7828395/
https://www.ncbi.nlm.nih.gov/pubmed/33450958
http://dx.doi.org/10.3390/toxins13010055