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Controversy of Peptide Cyclization from Tripeptide

The present investigation reports an attempt to synthesize naturally occurring α-cyclic tripeptide cyclo(Gly-l-Pro-l-Glu) 1, [cyclo(GPE)], previously isolated from the Ruegeria strain of bacteria with marine sponge Suberites domuncula. Three linear precursors, Boc-GPE(OBn)(2), Boc-PE(OBn)G and Boc-E...

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Detalles Bibliográficos
Autores principales: Lin, Chung-Yin, Chakraborty, Subrata, Wong, Chia-Wei, Tai, Dar-Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7828492/
https://www.ncbi.nlm.nih.gov/pubmed/33451079
http://dx.doi.org/10.3390/molecules26020389