A Perspective on Natural and Nature-Inspired Small Molecules Targeting Phosphodiesterase 9 (PDE9): Chances and Challenges against Neurodegeneration

As life expectancy increases, dementia affects a growing number of people worldwide. Besides current treatments, phosphodiesterase 9 (PDE9) represents an alternative target for developing innovative small molecules to contrast neurodegeneration. PDE inhibition promotes neurotransmitter release, amel...

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Detalles Bibliográficos
Autores principales: Ribaudo, Giovanni, Memo, Maurizio, Gianoncelli, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7828511/
https://www.ncbi.nlm.nih.gov/pubmed/33451065
http://dx.doi.org/10.3390/ph14010058

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7828511/
https://www.ncbi.nlm.nih.gov/pubmed/33451065
http://dx.doi.org/10.3390/ph14010058

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