QbD Enabled Azacitidine Loaded Liposomal Nanoformulation and Its In Vitro Evaluation

Azacitidine (AZA), an inhibitor of DNA methyltransferase, is a commonly recognized drug used in clinical treatment for myelodysplastic syndrome and breast cancer. Due to higher aqueous solubility and negative log P of AZA causes poor cancer cell permeation and controlled release. The objective of th...

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Detalles Bibliográficos
Autores principales: Kesharwani, Prashant, Md, Shadab, Alhakamy, Nabil A., Hosny, Khaled M., Haque, Anzarul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7828524/
https://www.ncbi.nlm.nih.gov/pubmed/33451016
http://dx.doi.org/10.3390/polym13020250

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7828524/
https://www.ncbi.nlm.nih.gov/pubmed/33451016
http://dx.doi.org/10.3390/polym13020250

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