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QbD Enabled Azacitidine Loaded Liposomal Nanoformulation and Its In Vitro Evaluation
Azacitidine (AZA), an inhibitor of DNA methyltransferase, is a commonly recognized drug used in clinical treatment for myelodysplastic syndrome and breast cancer. Due to higher aqueous solubility and negative log P of AZA causes poor cancer cell permeation and controlled release. The objective of th...
Autores principales: | Kesharwani, Prashant, Md, Shadab, Alhakamy, Nabil A., Hosny, Khaled M., Haque, Anzarul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7828524/ https://www.ncbi.nlm.nih.gov/pubmed/33451016 http://dx.doi.org/10.3390/polym13020250 |
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