Cargando…

The Taming of Nuclear Factor Erythroid-2-Related Factor-2 (Nrf2) Deglycation by Fructosamine-3-Kinase (FN3K)-Inhibitors-A Novel Strategy to Combat Cancers

SIMPLE SUMMARY: Aim of this review is to provide an overview on (a) Fructosamine-3-Kinase (FN3K) and its role in regulating Nuclear Factor Erythorid-2-Related Factor-2 (Nrf2); (b) the role of glycation and deglycation mechanisms in modulating the functional properties of proteins, in particular, the...

Descripción completa

Detalles Bibliográficos
Autores principales: Beeraka, Narasimha M., Bovilla, Venugopal R., Doreswamy, Shalini H., Puttalingaiah, Sujatha, Srinivasan, Asha, Madhunapantula, SubbaRao V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7828646/
https://www.ncbi.nlm.nih.gov/pubmed/33466626
http://dx.doi.org/10.3390/cancers13020281