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Inhibition of the Lipid Droplet–Peroxisome Proliferator-Activated Receptor α Axis Suppresses Cancer Stem Cell Properties

Cancer stem cells (CSCs), having both self-renewal and tumorigenic capacity, utilize an energy metabolism system different from that of non-CSCs. Lipid droplets (LDs) are organelles that store neutral lipids, including triacylglycerol. Previous studies demonstrated that LDs are formed and store lipi...

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Detalles Bibliográficos
Autores principales: Kuramoto, Kenta, Yamamoto, Masahiro, Suzuki, Shuhei, Togashi, Keita, Sanomachi, Tomomi, Kitanaka, Chifumi, Okada, Masashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7828779/
https://www.ncbi.nlm.nih.gov/pubmed/33466690
http://dx.doi.org/10.3390/genes12010099