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SequencErr: measuring and suppressing sequencer errors in next-generation sequencing data

BACKGROUND: There is currently no method to precisely measure the errors that occur in the sequencing instrument/sequencer, which is critical for next-generation sequencing applications aimed at discovering the genetic makeup of heterogeneous cellular populations. RESULTS: We propose a novel computa...

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Detalles Bibliográficos
Autores principales: Davis, Eric M., Sun, Yu, Liu, Yanling, Kolekar, Pandurang, Shao, Ying, Szlachta, Karol, Mulder, Heather L., Ren, Dongren, Rice, Stephen V., Wang, Zhaoming, Nakitandwe, Joy, Gout, Alexander M., Shaner, Bridget, Hall, Salina, Robison, Leslie L., Pounds, Stanley, Klco, Jeffery M., Easton, John, Ma, Xiaotu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7829059/
https://www.ncbi.nlm.nih.gov/pubmed/33487172
http://dx.doi.org/10.1186/s13059-020-02254-2