Nitrosonium Cation as a Cytotoxic Component of Dinitrosyl Iron Complexes with Thiol-containing Ligands (based on the Experimental Work on MCF7 Human Breast Cancer Cell Culture)

Here we demonstrate that binuclear dinitrosyl iron complexes with thiol-containing ligands (glutathione and mercaptosuccinate, B-DNIC-GSH and B-DNIC-MS, respectively) exert cytotoxic effects on MCF7 human breast cancer cells. We showed that they are mediated by nitrosonium cations released from thes...

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Detalles Bibliográficos
Autores principales: Vanin, Anatoly F., Tronov, Viktor A., Borodulin, Rostislav R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7829092/
https://www.ncbi.nlm.nih.gov/pubmed/33492647
http://dx.doi.org/10.1007/s12013-020-00962-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7829092/
https://www.ncbi.nlm.nih.gov/pubmed/33492647
http://dx.doi.org/10.1007/s12013-020-00962-x

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