Cargando…

Nitrosonium Cation as a Cytotoxic Component of Dinitrosyl Iron Complexes with Thiol-containing Ligands (based on the Experimental Work on MCF7 Human Breast Cancer Cell Culture)

Here we demonstrate that binuclear dinitrosyl iron complexes with thiol-containing ligands (glutathione and mercaptosuccinate, B-DNIC-GSH and B-DNIC-MS, respectively) exert cytotoxic effects on MCF7 human breast cancer cells. We showed that they are mediated by nitrosonium cations released from thes...

Descripción completa

Detalles Bibliográficos
Autores principales:	Vanin, Anatoly F., Tronov, Viktor A., Borodulin, Rostislav R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2021
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7829092/ https://www.ncbi.nlm.nih.gov/pubmed/33492647 http://dx.doi.org/10.1007/s12013-020-00962-x

Ejemplares similares

Dinitrosyl Iron Complexes with Thiol-Containing Ligands Can Suppress Viral Infections as Donors of the Nitrosonium Cation (Hypothesis)
por: Vanin, A. F.
Publicado: (2020)

How is Nitric Oxide (NO) Converted into Nitrosonium Cations (NO(+)) in Living Organisms? (Based on the Results of Optical and EPR Analyses of Dinitrosyl Iron Complexes with Thiol-Containing Ligands)
por: Vanin, Anatoly F.
Publicado: (2020)

Electronic and Spatial Structures of Water-Soluble Dinitrosyl Iron Complexes with Thiol-Containing Ligands Underlying Their Ability to Act as Nitric Oxide and Nitrosonium Ion Donors
por: Vanin, Anatoly F., et al.
Publicado: (2011)

The Cytostatic Action of Dinitrosyl Iron Complexes with Glutathione on Escherichia coli Cells Is Mediated by Nitrosonium Cations Released from These Complexes
por: Vanin, A. F., et al.
Publicado: (2022)

Positive (Regulatory) and Negative (Cytotoxic) Effects of Dinitrosyl Iron Complexes on Living Organisms
por: Vanin, Anatoly F.
Publicado: (2022)

Gaseous Nitric Oxide and Dinitrosyl Iron Complexes with Thiol-Containing Ligands as Potential Medicines that Can Relieve COVID-19
por: Vanin, A. F., et al.
Publicado: (2021)

Physico-Chemistry of Dinitrosyl Iron Complexes as a Determinant of Their Biological Activity †
por: Vanin, Anatoly F.
Publicado: (2021)

The Peroxidatic Thiol of Peroxiredoxin 1 is Nitrosated by Nitrosoglutathione but Coordinates to the Dinitrosyl Iron Complex of Glutathione
por: Truzzi, Daniela R., et al.
Publicado: (2020)

Beneficial Effects of Dinitrosyl Iron Complexes on Wound Healing Compared to Commercial Nitric Oxide Plasma Generator
por: Igrunkova, Alexandra, et al.
Publicado: (2023)

Antiviral Activity of Nitrosonium Cations against SARS-CoV-2 on a Syrian Hamster Model
por: Shipovalov, A. V., et al.
Publicado: (2022)

Protective Effect of Dinitrosyl Iron Complexes with Glutathione in Red Blood Cell Lysis Induced by Hypochlorous Acid
por: Shumaev, Konstantin B., et al.
Publicado: (2019)

Protective Effects of Dinitrosyl Iron Complexes under Oxidative Stress in the Heart
por: Kapelko, Valery I., et al.
Publicado: (2017)

Cytoprotective Effects of Dinitrosyl Iron Complexes on Viability of Human Fibroblasts and Cardiomyocytes
por: Akentieva, Natalia Pavlovna, et al.
Publicado: (2019)

Nitrosonium tetrafluoridoborate, NOBF(4)
por: Lozinšek, Matic
Publicado: (2021)

Protective Effect of Dinitrosyl Iron Complexes Bound with Hemoglobin on Oxidative Modification by Peroxynitrite
por: Kosmachevskaya, Olga V., et al.
Publicado: (2021)

Cell-Penetrating Delivery of Nitric Oxide by Biocompatible Dinitrosyl Iron Complex and Its Dermato-Physiological Implications
por: Chen, Yu-Chieh, et al.
Publicado: (2021)

Low molecular mass dinitrosyl nonheme-iron complexes up-regulate noradrenaline release in the rat tail artery
por: Kleschyov, Andrei L, et al.
Publicado: (2002)

Physiological Levels of Nitric Oxide Diminish Mitochondrial Superoxide. Potential Role of Mitochondrial Dinitrosyl Iron Complexes and Nitrosothiols
por: Dikalov, Sergey I., et al.
Publicado: (2017)

Endogenous Conjugation of Biomimetic Dinitrosyl Iron Complex with Protein Vehicles for Oral Delivery of Nitric Oxide to Brain and Activation of Hippocampal Neurogenesis
por: Wu, Cheng-Ru, et al.
Publicado: (2021)

Engineering proximal vs. distal heme–NO coordination via dinitrosyl dynamics: implications for NO sensor design
por: Kekilli, Demet, et al.
Publicado: (2017)

Nitrosonium nitrate (NO(+)NO(3) (−)) structure solution using in situ single-crystal X-ray diffraction in a diamond anvil cell
por: Laniel, Dominique, et al.
Publicado: (2021)

A Diferrous-Dinitrosyl Intermediate in the N(2)O-Generating Pathway of a Deflavinated Flavo-Diiron Protein
por: Caranto, Jonathan D., et al.
Publicado: (2014)

Intramolecular Metal Exchange Reaction Promoted by Thiol Ligands
por: Li, Yangfeng, et al.
Publicado: (2018)

Revisiting the Cytotoxicity of Cationic Polyelectrolytes as a Principal Component in Layer-by-Layer Assembly Fabrication
por: Naumenko, Ekaterina, et al.
Publicado: (2021)

Aerobic nitric oxide-induced thiol nitrosation in the presence and absence of magnesium cations
por: Kolesnik, Bernd, et al.
Publicado: (2014)

Reductive Cleavage of Organic Peroxides by Iron Salts and Thiols
por: Olson, Andrew S., et al.
Publicado: (2018)

H(2)S/Thiols, NO(•), and NO(–)/HNO: Interactions with Iron Porphyrins
por: Bieza, Silvina, et al.
Publicado: (2022)

Cytotoxic and chemomodulatory effects of Phyllanthus niruri in MCF-7 and MCF-7(ADR) breast cancer cells
por: Abdel-Sattar, Ola E., et al.
Publicado: (2023)

Cytotoxic and apoptogenic effect of hypericin, the bioactive component of Hypericum perforatum on the MCF-7 human breast cancer cell line
por: Mirmalek, Seyed Abbas, et al.
Publicado: (2016)

Interaction of Cationic Carbosilane Dendrimers and Their siRNA Complexes with MCF-7 Cells
por: Białkowska, Kamila, et al.
Publicado: (2021)

Reversible Dissociation and Ligand-Glutathione Exchange Reaction in Binuclear Cationic Tetranitrosyl Iron Complex with Penicillamine
por: Syrtsova, Lidia, et al.
Publicado: (2014)

Comparison of cytotoxicity and genotoxicity of 4-hydroxytamoxifen in combination with Tualang honey in MCF-7 and MCF-10A cells
por: Yaacob, Nik Soriani, et al.
Publicado: (2014)

Iron and thiols as two major players in carcinogenesis: friends or foes?
por: Toyokuni, Shinya
Publicado: (2014)

Role of Metal Cations of Copper, Iron, and Aluminum and Multifunctional Ligands in Alzheimer’s Disease: Experimental and Computational Insights
por: Puentes-Díaz, Nicolás, et al.
Publicado: (2023)

Cytotoxicity and Genotoxicity Assessment of Sandalwood Essential Oil in Human Breast Cell Lines MCF-7 and MCF-10A
por: Ortiz, Carmen, et al.
Publicado: (2016)

In vitro cytotoxicity analysis of doxorubicin-loaded/superparamagnetic iron oxide colloidal nanoassemblies on MCF7 and NIH3T3 cell lines
por: Tomankova, Katerina, et al.
Publicado: (2015)

Cinchona officinalis Phytochemicals-Loaded Iron Oxide Nanoparticles Induce Cytotoxicity and Stimulate Apoptosis in MCF-7 Human Breast Cancer Cells
por: Al-Harbi, Laila Naif, et al.
Publicado: (2022)

Lawsone Derivatives as Efficient Photopolymerizable Initiators for Free-Radical, Cationic Photopolymerizations, and Thiol—Ene Reactions
por: Elian, Christine, et al.
Publicado: (2021)

Radical‐Mediated Thiol‐Ene Strategy: Photoactivation of Thiol‐Containing Drugs in Cancer Cells
por: Sun, Shuang, et al.
Publicado: (2018)

The Influence of Cationic Nitrosyl Iron Complex with Penicillamine Ligands on Model Membranes, Membrane-Bound Enzymes and Lipid Peroxidation
por: Poletaeva, Darya A., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_if44tma9n36rm4nrfp1ae5eimb