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PhenoMapping: a protocol to map cellular phenotypes to metabolic bottlenecks, identify conditional essentiality, and curate metabolic models

Targeted identification of cellular processes responsible for a phenotype is of major importance in guiding efforts in bioengineering and medicine. Genome-scale metabolic models (GEMs) are widely used to integrate various types of omics data and study the cellular physiology under different conditio...

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Detalles Bibliográficos
Autores principales: Chiappino-Pepe, Anush, Hatzimanikatis, Vassily
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7829271/
https://www.ncbi.nlm.nih.gov/pubmed/33532729
http://dx.doi.org/10.1016/j.xpro.2020.100280