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Generation and assessment of high-quality mouse oocytes and embryos following nicotinamide mononucleotide administration

The low quality of oocytes is one of the main causes of the suboptimal reproductive outcome of female mammals with advanced maternal age. Here, we present a detailed protocol to obtain high-quality oocytes and embryos from aged mice by nicotinamide mononucleotide (NMN) administration. We also descri...

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Detalles Bibliográficos
Autores principales: Miao, Yilong, Chen, Jingyue, Gao, Qian, Xiong, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7829339/
https://www.ncbi.nlm.nih.gov/pubmed/33532742
http://dx.doi.org/10.1016/j.xpro.2021.100298