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Generation and assessment of high-quality mouse oocytes and embryos following nicotinamide mononucleotide administration
The low quality of oocytes is one of the main causes of the suboptimal reproductive outcome of female mammals with advanced maternal age. Here, we present a detailed protocol to obtain high-quality oocytes and embryos from aged mice by nicotinamide mononucleotide (NMN) administration. We also descri...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7829339/ https://www.ncbi.nlm.nih.gov/pubmed/33532742 http://dx.doi.org/10.1016/j.xpro.2021.100298 |