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Quantification of drug-induced fractional killing using high-throughput microscopy

Anti-cancer drugs kill only a fraction of cells within a population at any given time. Here, we describe a protocol to quantify drug-induced fractional killing over time using high-throughput imaging. This protocol can be used to compare the effect of hundreds of conditions in parallel. We show how...

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Detalles Bibliográficos
Autores principales: Inde, Zintis, Rodencal, Jason, Dixon, Scott J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7829341/
https://www.ncbi.nlm.nih.gov/pubmed/33532743
http://dx.doi.org/10.1016/j.xpro.2021.100300