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Astragalin Alleviates Neuropathic Pain by Suppressing P2X4-Mediated Signaling in the Dorsal Root Ganglia of Rats

Neurologic damage often leads to neuropathic pain, for which there are no effective treatments owing to its complex pathogenesis. The purinergic receptor P2X4 is closely associated with neuropathic pain. Astragalin (AST), a compound that is used in traditional Chinese medicine, has protective effect...

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Detalles Bibliográficos
Autores principales: Wang, Mengke, Cai, Xia, Wang, Yueying, Li, Shizhen, Wang, Na, Sun, Rui, Xing, Jingming, Liang, Shangdong, Liu, Shuangmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7829479/
https://www.ncbi.nlm.nih.gov/pubmed/33505232
http://dx.doi.org/10.3389/fnins.2020.570831