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Extracellular Vesicle-Derived microRNA-410 From Mesenchymal Stem Cells Protects Against Neonatal Hypoxia-Ischemia Brain Damage Through an HDAC1-Dependent EGR2/Bcl2 Axis

Hypoxia-ischemia brain damage (HIBD) is a neurological disorder occring in neonates, which is exacerbated by neuronal apoptosis. Mesenchymal stem cells (MSCs)-derived extracellular vesicles (EVs) have been proposed as a promising strategy for treating or preventing ischemia-related diseases. However...

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Detalles Bibliográficos
Autores principales: Han, Jun, Yang, Si, Hao, Xiaosheng, Zhang, Bo, Zhang, Hongbo, Xin, Cuijuan, Hao, Yunpeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7829500/
https://www.ncbi.nlm.nih.gov/pubmed/33505958
http://dx.doi.org/10.3389/fcell.2020.579236