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Probabilistic harmonization and annotation of single‐cell transcriptomics data with deep generative models

As the number of single‐cell transcriptomics datasets grows, the natural next step is to integrate the accumulating data to achieve a common ontology of cell types and states. However, it is not straightforward to compare gene expression levels across datasets and to automatically assign cell type l...

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Detalles Bibliográficos
Autores principales: Xu, Chenling, Lopez, Romain, Mehlman, Edouard, Regier, Jeffrey, Jordan, Michael I, Yosef, Nir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7829634/
https://www.ncbi.nlm.nih.gov/pubmed/33491336
http://dx.doi.org/10.15252/msb.20209620