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Identification of the New In Vivo Metabolites of Ilaprazole in Rat Plasma after Oral Administration by LC-MS: In Silico Prediction of the H(+)/K(+)-ATPase Inhibitor

Ilaprazole is a proton pump inhibitor used to treat digestive diseases. In this study, blood samples were collected after oral administration of ilaprazole and prepared by liquid–liquid extraction. The metabolites of ilaprazole were detected by liquid chromatography–high-resolution mass spectrometry...

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Detalles Bibliográficos
Autores principales: Zhang, Guiqiu, Guo, Kaijing, Wang, Pengfei, Shan, Yingbo, Ma, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7829900/
https://www.ncbi.nlm.nih.gov/pubmed/33467211
http://dx.doi.org/10.3390/molecules26020459