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Identification of the New In Vivo Metabolites of Ilaprazole in Rat Plasma after Oral Administration by LC-MS: In Silico Prediction of the H(+)/K(+)-ATPase Inhibitor
Ilaprazole is a proton pump inhibitor used to treat digestive diseases. In this study, blood samples were collected after oral administration of ilaprazole and prepared by liquid–liquid extraction. The metabolites of ilaprazole were detected by liquid chromatography–high-resolution mass spectrometry...
Autores principales: | Zhang, Guiqiu, Guo, Kaijing, Wang, Pengfei, Shan, Yingbo, Ma, Chen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7829900/ https://www.ncbi.nlm.nih.gov/pubmed/33467211 http://dx.doi.org/10.3390/molecules26020459 |
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